86884-89-1

Basic information

• Product Name: 2-Methyl-2,3-epoxy-1-propanol
• Synonyms: (2r)-2-methyl-oxiranemethanol;2-Methyl-2,3-epoxy-1-propanol;(R)-2-Methyl glycidol;2-methylglycidol;(R)-2-Methylglycidol,97%;(R)-(2-methyloxiran-2-yl)methanol;(2R)-methylglycidol;(2-Methyl-oxiranyl)-methanol
• CAS NO: 86884-89-1
• Molecular Formula: C₄H₈O₂
• Molecular Weight: 88.11
• Product Categories: Industrial/Fine Chemicals
• Mol File: 86884-89-1.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 107°C (estimate)
• Flash Point: 62.8 °C
• Appearance: clear colourless liquid
• Density: 1.1000
• Vapor Pressure: 2.34mmHg at 25°C
• Refractive Index: 1.4750 (estimate)
• PKA: 14.44±0.10(Predicted)
• CAS DataBase Reference: 2-Methyl-2,3-epoxy-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-2,3-epoxy-1-propanol(86884-89-1)
• EPA Substance Registry System: 2-Methyl-2,3-epoxy-1-propanol(86884-89-1)

Safety Data

• Hazardous Substances Data: 86884-89-1(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLOURLESS LIQUID

InChI:InChI=1/C4H8O2/c1-4(2-5)3-6-4/h5H,2-3H2,1H3

Upstream product

• 872-30-0 2-methylglycidol 
• 118200-96-7 (2S)-methyl-3-[4-nitrobenzoyl(oxy)]-1,2-epoxy-propane 
• 513-42-8 3-hydroxy-2-methyl-1-propene 
• 133868-47-0 (R)-2,3-dihydroxy-2-methylpropyl p-toluenesulfonate 

Downstream Products

• 118088-01-0 1-((S)-2-Methyl-oxiranyl)-3-phenyl-propan-1-ol 
• 118088-08-7 1-((S)-2-Methyl-oxiranyl)-1-p-tolyl-prop-2-yn-1-ol 
• 184091-30-3 (S)-1-(tert-butyldiphenylsilyloxy)methyl-1-methyloxirane 
• 683276-63-3 [(2S)-2-methyloxiran-2-yl]methyl 4-nitrobenzene-1-sulfonate 
• 152218-31-0 (S)-(2-methyloxiran-2-yl)methyl 3-nitrobenzenesulfonate 
• 118200-96-7 (2S)-methyl-3-[4-nitrobenzoyl(oxy)]-1,2-epoxy-propane 
• 106268-96-6 (2R)-methyl-3-[4-nitrobenzoyl(oxy)]-1,2-epoxy-propane 
• 116216-91-2 (S)-2-benzyloxymethyl-2-methyloxirane 
• 86884-91-5 (R)-(-)-2-methyl-1-(phenylthio)-2,3-propanediol 

Relevant articles and documents

SYNTHESIS OF NATURAL AND UNNATURAL FRONTALIN

(S)-(-)- and (R)-(+)-Frontalin were synthesized, respectively, in high enantiomer excess from β-methallyl alcohol (2) by three-step procedure; (i) asymmetric epoxidation of 2, (ii) the epoxide opening with homoallylmagnesium bromide, and (iii) Pd(II)-catalyzed intramolecular acetalization.

Nitroimidazole compound as well as preparation method and application thereof

The invention discloses a novel nitroimidazole compound as well as a preparation method and application thereof. The nitroimidazole compound has a general formula (I) shown in the specification.

Novel pathway for the synthesis of arylpropionamide-derived selective androgen receptor modulator (SARM) metabolites of andarine and ostarine

O-Dephenylandarine and O-dephenylostarine, two SARM metabolites relevant for doping control analysis, were synthesized in their endogenous (S)-forms as well as in terms of their racemates. The enantiopure (S)-metabolites were obtained after six steps in 20% and 23% overall yield, the slightly modified racemic route provided the compounds in 28% and 31% total yield, respectively.