872047-95-5Relevant academic research and scientific papers
Trans-1-sulfonylamino-2-isoborneolsulfonylaminocyclohexane derivatives: Excellent chiral ligands for the catalytic enantioselective addition of organozinc reagents to ketones
Forrat, Vicente J.,Prieto, Oscar,Ramon, Diego J.,Yus, Miguel
, p. 4431 - 4445 (2008/02/08)
The catalytic enantioselective addition of different organozinc reagents (such as alkyl and aryl derivatives or in situ generated aryl, allyl alkenyl, and alkynyl derivatives obtained through different transmetallation processes) to simple ketones has bee
Chiral tertiary alcohols from a trans-1-arenesulfonyl-amino-2- isoborneolsulfonylaminocyclohexane-catalyzed addition of organozincs to ketones
Forrat, Vicente J.,Ramon, Diego J.,Yus, Miguel
, p. 3341 - 3344 (2007/10/03)
The catalytic enantioselective addition of different organozinc reagents, such as alkyl, or in situ generated aryl, allyl, alkenyl and alkynyl derivatives to simple aryl ketones, was accomplished using titanium tetraisopropoxide and chiral ligands derived from 1-arenesulfonylamino-2- isoborneolsulfonylamidocyclohexane, giving the corresponding tertiary alcohols with enantioselectivities up to ≥99%. A simple and efficient procedure for the synthesis of the disulfonamide ligands used is described.
