872050-98-1

Basic information

• Product Name: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(5-methoxy-2-(methoxymethoxy)phenyl)butan-2-one
• Synonyms: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(5-methoxy-2-(methoxymethoxy)phenyl)butan-2-one
• CAS NO: 872050-98-1
• Molecular Weight: 404.46
• Mol File: 872050-98-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(5-methoxy-2-(methoxymethoxy)phenyl)butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(5-methoxy-2-(methoxymethoxy)phenyl)butan-2-one(872050-98-1)
• EPA Substance Registry System: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(5-methoxy-2-(methoxymethoxy)phenyl)butan-2-one(872050-98-1)

Safety Data

• Hazardous Substances Data: 872050-98-1(Hazardous Substances Data)

Upstream product

• 73220-26-5 1-methoxy-2-(methoxymethoxy)benzene 
• 584-82-7 2-allyl-4-methoxyphenol 
• 13391-35-0 allyl (4-methoxyphenyl) ether 
• 944389-16-6 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(5-methoxy-2-(methoxymethoxy)phenyl)but-3-yn-2-ol 
• 944389-17-7 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(5-methoxy-2-(methoxymethoxy)phenyl)butan-2-ol 
• 634153-28-9 4-[(3-methoxy)-2-(methoxymethoxy)phenyl]-2-methylbutyn-3-yn-2-ol 
• 634153-25-6 1-ethynyl-3-metyhoxy-2-(2-methoxymethoxy)benzene 
• 634153-26-7 2-allyl-4-methoxy-1-(methoxymethoxy)benzene 
• 634153-23-4 2-(5-methoxy-2-(methoxymethoxy)phenyl)acetaldehyde 
• 165071-94-3 1-iodo-3-methoxy-2-(methoxymethoxy)benzene 
• 90-05-1 2-methoxy-phenol 
• 150-76-5 4-methoxy-phenol 

Relevant articles and documents

Synthesis of aromatic spiroacetals related to γ-rubromycin based on a 3H-spiro[1-benzofuran-2,2′-chromane] skeleton

The synthesis of a series of aromatic 5,6-benzannelated and naphthyl-benzannelated spiroacetals related to the spiroacetal unit present in the quinonoid antibiotic γ-rubromycin is reported. The key steps include the use of Sonogashira coupling to construct an aryl acetylene that is coupled to an aryl aldehyde forming a propargyl alcohol intermediate. Hydrogenation of the resultant alkynol followed by oxidation produces a masked dihydroxyketone that upon treatment with silica-supported sodium hydrogen sulfate undergoes concomitant deprotection and cyclisation to afford the desired fused aromatic spiroacetal.