872329-48-1

Basic information

• Product Name: chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate
• Synonyms: chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate
• CAS NO: 872329-48-1
• Molecular Weight: 384.822
• Mol File: 872329-48-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate(872329-48-1)
• EPA Substance Registry System: chloromethyl 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylate(872329-48-1)

Safety Data

• Hazardous Substances Data: 872329-48-1(Hazardous Substances Data)

Upstream product

• 872329-95-8 1-ethyl-6-oxo-3-phenyl-5-(pyridin-3-ylamino)-1,6-dihydropyridazine-4-carboxylic acid 
• 49715-04-0 chlorosulfuric acid chloromethyl ester 
• 872329-70-9 5-amino-1-ethyl-6-oxo-3-phenyl-1,6-dihydro-pyridazine-4-carboxylic acid ethyl ester 
• 626-55-1 3-Bromopyridine 

Relevant articles and documents

PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS

The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives, to processes for their preparation and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention and suppression of related pathological conditions, diseases and disorders, in particular asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, topic dermatitis, psoriasis or irritable bowel disease.