87241-90-5Relevant academic research and scientific papers
Synthesis of Racemates and (+)-Enantiomers of γ-Caprolactone, γ-Dodecanolactone and δ-Hexadecanolactone, Lactonic Sex Pheromones of the Dermestid Beetle, Rove Beetle and Oriental Hornet
Naoshima, Yoshinobu,Ozawa, Hiroshi,Kondo, Hirokiyo,Hayashi, Shuichi
, p. 1431 - 1434 (2007/10/02)
A simple method based on regioselective two-step alkylation of easily-available diethyl 3-oxoglutarate (2) is described for the synthesis of racemates of the lactonic pheromones, 1a, 1b, and 1c.Their (+)-enantiomers were also synthesized by means of microbiological reduction of the intermediary keto acids.
