87243-54-7Relevant academic research and scientific papers
ACETALS OF LACTAMS AND AMIDES. 42. REACTIONS OF ENAMINO AMIDES AND ENAMINO ESTERS WITH SOME FORMYLATING AGENTS. SYNTHESIS OF DERIVATIVES OF 2-PYRIDONE AND OF PYRIMIDIN-4- AND -6-ONES
Granik, V. G.,Ershov, L. V.,Grizik, S. I.,Chistyakov, V. V.
, p. 1026 - 1031 (2007/10/02)
The reactions of enamino esters and enamino amides with the diethyl acetal of dimethylformamide and with orthoformic ester have been investigated and it has been shown that the process takes place in two directions - with the formation of pyrimidone or 2-
ACETALS OF LACTAMS AND ACID AMIDES. 38. SYNTHESIS OF PYRIMIDINE AND PYRIDINE DERIVATIVES ON THE BASIS OF THE REACTION OF ENAMINO AMIDES WITH AMIDE ACETALS
Granik, V. G.,Kaimanakova, S. I.
, p. 657 - 661 (2007/10/02)
Derivatives of 1-benzyl-4-pyrimidinones and 1-benzyl-6-pyrimidinones were synthesized by the reaction of α-cyano-β-N-benzylaminocrotonamide and α-cyano-β-aminocrotonic acid N-benzylamine with dimethylformamide diethylacetal.When 1-benzyl-5-cyano-6-(β-dimethylamino)vinyl-1,6-dihydro-4-pyrimidinone is heated in an alkaline medium, it is converted to 3-cyano-4-benzylamino-2-pyridone, from which a pyridopyrimidine derivative was synthesized.When 1-benzyl-5-cyano-4-(β-dimethylamino)vinyl-1,6-dihydro-6-pyrimidinone is heated in alkaline solution, it is converted to α-cyano-β-hydroxycrotonic acid N-benzylamide.
