87243-52-5

Upstream product

• 10412-93-8 N-Benzylcyanoacetamide 
• 19429-85-7 N,N-dimethylacetamide diethyl acetal 

Downstream Products

• 87243-55-8 α-Cyano-β-hydroxycrotonic Acid N-Benzylamide 
• 87243-53-6 benzylamide of β-amino-α-cyanocrotonic acid 
• 87243-54-7 1-Benzyl-4-(β-N,N-dimethylaminovinyl)-5-cyano-1,6-dihydro-6-pyrimidinone 
• 95309-98-1 1-benzyl-3-cyano-4-dimethylamino-2-pyridone 
• 87164-98-5 (Z)-N-Benzyl-2-cyano-3-dimethylamino-acrylamide 

Relevant academic research and scientific papers

ACETALS OF LACTAMS AND ACID AMIDES. 38. SYNTHESIS OF PYRIMIDINE AND PYRIDINE DERIVATIVES ON THE BASIS OF THE REACTION OF ENAMINO AMIDES WITH AMIDE ACETALS

Derivatives of 1-benzyl-4-pyrimidinones and 1-benzyl-6-pyrimidinones were synthesized by the reaction of α-cyano-β-N-benzylaminocrotonamide and α-cyano-β-aminocrotonic acid N-benzylamine with dimethylformamide diethylacetal.When 1-benzyl-5-cyano-6-(β-dimethylamino)vinyl-1,6-dihydro-4-pyrimidinone is heated in an alkaline medium, it is converted to 3-cyano-4-benzylamino-2-pyridone, from which a pyridopyrimidine derivative was synthesized.When 1-benzyl-5-cyano-4-(β-dimethylamino)vinyl-1,6-dihydro-6-pyrimidinone is heated in alkaline solution, it is converted to α-cyano-β-hydroxycrotonic acid N-benzylamide.