872550-10-2Relevant academic research and scientific papers
Synthesis of 3-alkyl naphthalenes as novel estrogen receptor ligands
Fang, Jing,Akwabi-Ameyaw, Adwoa,Britton, Jonathan E.,Katamreddy, Subba R.,Navas III, Frank,Miller, Aaron B.,Williams, Shawn P.,Gray, David W.,Orband-Miller, Lisa A.,Shearin, Jean,Heyer, Dennis
scheme or table, p. 5075 - 5077 (2009/05/07)
A series of estrogen receptor ligands based on a 3-alkyl naphthalene scaffold was synthesized using an intramolecular enolate-alkyne cycloaromatization as the key step. Several of these compounds bearing a C6-OH group were shown to be high affinity ligand
CHEMICAL COMPOUNDS
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Page/Page column 88, (2010/02/15)
The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel naphthalene compounds that are particularly useful for selective estrogen receptor modulation.
