133446-35-2Relevant academic research and scientific papers
Enantioselective Lactonization by π-Acid-Catalyzed Allylic Substitution: A Complement to π-Allylmetal Chemistry
Aponick, Aaron,Kizhakkayil Mangadan, Arun Raj,Liu, Ji
supporting information, p. 22224 - 22229 (2021/09/09)
Asymmetric allylic alkylation (AAA) is a powerful method for the formation of highly useful, non-racemic allylic compounds. Here we present a complementary enantioselective process that generates allylic lactones via π-acid catalysis. More specifically, a
Synthesis of 3-alkyl naphthalenes as novel estrogen receptor ligands
Fang, Jing,Akwabi-Ameyaw, Adwoa,Britton, Jonathan E.,Katamreddy, Subba R.,Navas III, Frank,Miller, Aaron B.,Williams, Shawn P.,Gray, David W.,Orband-Miller, Lisa A.,Shearin, Jean,Heyer, Dennis
scheme or table, p. 5075 - 5077 (2009/05/07)
A series of estrogen receptor ligands based on a 3-alkyl naphthalene scaffold was synthesized using an intramolecular enolate-alkyne cycloaromatization as the key step. Several of these compounds bearing a C6-OH group were shown to be high affinity ligand
CHEMICAL COMPOUNDS
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Page/Page column 87-88, (2010/02/15)
The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel naphthalene compounds that are particularly useful for selective estrogen receptor modulation.
Rhodium(II)-Catalyzed Cyclization Reactions of Alkynyl-Substituted α-Diazo Ketones
Padwa, Albert,Krumpe, Keith E.,Gareau, Yves,Chiacchio, Ugo
, p. 2523 - 2530 (2007/10/02)
Treatment of several o-alkynyl-substituted α-diazoacetophenone derivatives with rhodium(II) carboxylates results in the formation of substituted indenones.The simplest mechanism accounting for the results involves addition of a rhodium-stabilized carbenoi
