872703-58-7Relevant academic research and scientific papers
A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold
Ekegren, Jenny K.,Unge, Torsten,Safa, Mayada Zreik,Wallberg, Hans,Samuelsson, Bertil,Hallberg, Anders
, p. 8098 - 8102 (2007/10/03)
Novel HIV-1 protease inhibitors encompassing a tertiary alcohol as part of the transition-state mimicking unit have been synthesized. Variation of the P1′-P3′ residues and alteration of the tertiary alcohol absolute stereochemistry a
