87277-67-6

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 529-27-1 2-methylphenylhydrazine 

Downstream Products

• 87277-62-1 4-Isopropylidene-5-phenyl-2-o-tolyl-2,4-dihydro-pyrazol-3-one 
• 87277-57-4 4,6,6-Trimethyl-3-phenyl-1-o-tolyl-1,6-dihydro-pyrano[2,3-c]pyrazole 
• 1311144-31-6 C₃₃H₂₆N₄O₂ 
• 1315480-32-0 1-(2'-methylphenyl)-3-phenyl-4-formyl-2-pyrazolin-5-one 
• 1315480-38-6 1-(2'-methylphenyl)-3-phenyl-5-pyrrolidinopyrazole 
• 1315480-43-3 1-(2'-methylphenyl)-3-phenyl-5-piperidinopyrazole 
• 1245126-36-6 5-bromo-3-phenyl-1-o-tolyl-1H-pyrazole 
• 63637-58-1 3-phenyl-1-(4-methylphenyl)-1H-pyrazole 

Relevant academic research and scientific papers

Asymmetric [3 + 3] Annulation of Copper-Allenylidenes with Pyrazolones: Synthesis of Chiral 1,4-Dihydropyrano[2,3- c]pyrazoles

The copper-catalyzed asymmetric [3 + 3] annulation of ethynyl benzoxazinanones with pyrazolones has been achieved, providing simple access to 1,4-dihydropyrano[2,3-c]pyrazole derivatives in moderate to excellent yields with excellent enantioselectivities (up to 99% ee). Compared with previous annulation reactions of copper-allenylidenes from ethynyl benzoxazinanones, the current reaction fused the three carbon atoms of the propargyl moiety into a heterocyclic framework.