872832-01-4

Basic information

• Product Name: Benzoic acid, 4-methoxy-, (2E)-2,5-hexadienyl ester
• CAS NO: 872832-01-4
• Molecular Formula: C14H16O3
• Molecular Weight: 232.279
• Mol File: 872832-01-4.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-methoxy-, (2E)-2,5-hexadienyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-methoxy-, (2E)-2,5-hexadienyl ester(872832-01-4)
• EPA Substance Registry System: Benzoic acid, 4-methoxy-, (2E)-2,5-hexadienyl ester(872832-01-4)

Safety Data

• Hazardous Substances Data: 872832-01-4(Hazardous Substances Data)

Upstream product

• 28465-64-7 (E)-hexa-2,5-dien-1-ol 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 872832-02-5 4-methoxybenzoic acid (2R,3R)-2,3-dihydroxyhex-5-enyl ester 

Relevant articles and documents

Asymmetric total synthesis of the 1-epi-aglycon of the cripowellins A and B

The unusual [5.3.2]-bicyclic structure of the insecticidal Amaryllidaceae alkaloids cripowellin A (1) and B (2) has been synthesized for the first time via a sequence of Sharpless dihydroxylation, ring-closing metathesis, and intramolecular Heck reaction. The asymmetric synthesis of the 1-epi-aglycon 82 proceeds with virtually complete diastereo- and enantioselectivity (de, ee ≥ 98%) in 13 steps and an overall yield of 5.6%. In addition, three alternative approaches toward the aglycon 3 are also described focusing on (1) the alkylation of the 2-benzazepinedithianes 35 and 36 with the electrophile 11, (2) a radical cyclization of the precursor (R/S,S,S)-39, and (3) an intramolecular arylation reaction of the aryl ketone 47.