872880-45-0Relevant academic research and scientific papers
Proline-catalyzed, asymmetric Mannich reactions in the synthesis of a DPP-IV inhibitor
Janey, Jacob M.,Hsiao, Yi,Armstrong III, Joseph D.
, p. 390 - 392 (2007/10/03)
A highly stereoselective L-proline-catalyzed, asymmetric direct Mannich reaction between a glyoxalate-derived imine and phenyl acetaldehyde was employed for the formation of a syn substituted β-phenyl homoserine. This Mannich adduct was then readily elabo
