87292-26-0Relevant academic research and scientific papers
Stereo- and Chemo-Selectivity in reduction of α-alkyl Aryl Ketones with Metal Hydrides
Aoki, Ikuo,Nishibayashi,Uemura, Sakae
, p. 337 - 340 (2007/10/02)
Metal hydride reduction of a variety of α-alkyl aryl ketones gives a mixture of threo- and erythro-β-aryl-β-hydroxyalkyl phenyl(or methyl)selenides by carbonyl reduction and 1-aryl-1-alkanol by the substitution of a phenyl(or methyl)seleno group with hydrogen.With all metal hydrides examined the formation of the threo-isomer always predominated.The addition of various metal chlorides in the reduction of various α-heteroatom (N, P, O, S)-substituted ketones.
Preparation of 2-Arylpropanoic Acids by Oxidative Aryl Migration in (β-Aryl-β-hydroxy)alkyl Phenyl Selenides
Uemura, Sakae,Ohe, Kouichi,Yamauchi, Takayoshi,Mizutaki, Shoichi,Tamaki, Kentaro
, p. 907 - 910 (2007/10/02)
Oxidation of diastereomeric mixtures of 1-aryl-1-hydroxyprop-2-yl phenyl selenides, prepared either by phenylselenylation of propiophenones followed by reduction or by treatment of benzaldehyde with α-(phenylseleno)ethyl anion, with an excess of meta-chloroperbenzoic acid in methanol at 25 deg C for 24 h or at reflux for 2 h affords methyl 2-arylpropanoates almost quantitatively.Similar treatment in tetrahydrofuran at 25 deg C for 24 h results in a direct formation of 2-arylpropanoic acids in high yields.
NOVEL PHOTOREDUCTIVE ALKYLATION OF METHYL 4-PHENYLBENZOATE WITH ALIPHATIC TERTIARY AMINES
Tsujimoto, Kazuo,Inaba, Yoshihiro,Ohashi, Mamoru
, p. 1113 - 1116 (2007/10/02)
A photoinduced electron-transfer reaction of methyl 4-phenylbenzoate with triethylamine leads to an aminoketone (4), and a photoreductive ethylation product (2) which results from the Norrish Type II reaction of the aminoketone.
