91306-52-4

Basic information

• Product Name: 1-Propanone, 1-[1,1'-biphenyl]-4-yl-2-(phenylseleno)-
• CAS NO: 91306-52-4
• Molecular Formula: C21H18OSe
• Molecular Weight: 365.333
• Mol File: 91306-52-4.mol

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-[1,1'-biphenyl]-4-yl-2-(phenylseleno)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-[1,1'-biphenyl]-4-yl-2-(phenylseleno)-(91306-52-4)
• EPA Substance Registry System: 1-Propanone, 1-[1,1'-biphenyl]-4-yl-2-(phenylseleno)-(91306-52-4)

Safety Data

• Hazardous Substances Data: 91306-52-4(Hazardous Substances Data)

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 37940-57-1 1-biphenyl-4-yl-propan-1-one 

Downstream Products

• 87292-26-0 1-([1,1'-biphenyl]-4-yl)propan-1-ol 
• 116333-30-3 1-Biphenyl-4-yl-2-phenylselanyl-propan-1-ol 
• 116333-30-3 1-Biphenyl-4-yl-2-phenylselanyl-propan-1-ol 

Relevant articles and documents

New Preparative Method for 2-Arylpropanoic Acids by Oxidative Aryl Migration in Aryl α-Seleno- and Aryl α-Telluro-ethyl Ketones

Oxidation with m-chloroperbenzoic acid of the ethylene acetals of aryl α-phenylseleno- or aryl α-phenyltelluro-ethyl ketones prepared by treating the corresponding α-bromo compounds with diphenyl diselenide-sodium or diphenyl ditelluride-sodium, respectively, affords hydroxyethyl 2-arylpropanoates in moderate to good yields via aryl group migration.

Stereo- and Chemo-Selectivity in reduction of α-alkyl Aryl Ketones with Metal Hydrides

Metal hydride reduction of a variety of α-alkyl aryl ketones gives a mixture of threo- and erythro-β-aryl-β-hydroxyalkyl phenyl(or methyl)selenides by carbonyl reduction and 1-aryl-1-alkanol by the substitution of a phenyl(or methyl)seleno group with hydrogen.With all metal hydrides examined the formation of the threo-isomer always predominated.The addition of various metal chlorides in the reduction of various α-heteroatom (N, P, O, S)-substituted ketones.

Preparation of 2-Arylpropanoic Acids by Oxidative Aryl Migration in (β-Aryl-β-hydroxy)alkyl Phenyl Selenides

Oxidation of diastereomeric mixtures of 1-aryl-1-hydroxyprop-2-yl phenyl selenides, prepared either by phenylselenylation of propiophenones followed by reduction or by treatment of benzaldehyde with α-(phenylseleno)ethyl anion, with an excess of meta-chloroperbenzoic acid in methanol at 25 deg C for 24 h or at reflux for 2 h affords methyl 2-arylpropanoates almost quantitatively.Similar treatment in tetrahydrofuran at 25 deg C for 24 h results in a direct formation of 2-arylpropanoic acids in high yields.