873-57-4Relevant articles and documents
Synthesis of (Bi1-xSbx)2S3 solid solutions via thermal decomposition of bismuth and antimony piperidinedithiocarbamates
Kun, Walter N.,McNaughter, Paul D.,Nyamen, Linda D.,Spencer, Ben F.,O'Brien, Paul,Ndifon, Peter T.,Revaprasadu, Neerish
, p. 15836 - 15844 (2019)
The synthesis of the complete range of (Bi1-xSbx)2S3 solid solutions, where 0 ≤ x ≤ 1, by the variation of the mole ratio of bismuth and antimony piperidine dithiocarbamate complexes is reported. There was a near linear expansion of a and c lattice parameters as the mole ratio of the antimony precursor was increased. The composition of the particles directionally followed the amount of precursor ratio used. When the composition of particles was compared to cell parameters, a slight deviation from Vegard's law was observed with a corresponding contraction of the b parameter and an approximately 3.5% reduction of the lattice volume. The nanorods obtained showed aspect ratios that depend on the composition of the material. The Bi and Sb rich materials had high aspect ratios of 16.58 and 16.58 respectively with a minimum aspect ratio of 2.58 observed for x = 0.50.
Functionalised trimethyltetrathiafulvalene (TriMe-TTF) derivatives via reactions of trimethyltetrathiafulvalenyllithium with electrophiles: X-ray crystal structures of benzoyl-TriMe-TTF and benzoylthio-TriMe-TTF
Moore,Bryce,Batsanov,Cole,Howard
, p. 675 - 682 (1995)
A high yielding synthesis of trimethyltetrathiafulvalene is reported and a range of functionalised derivatives have been prepared via reactions of trimethyltetrathiafulvalenyllithium with electrophiles.
The syntheses and structures of Zn(II) heterocyclic piperidine and tetrahydroquinoline dithiocarbamates and their use as single source precursors for ZnS nanoparticles
Nyamen, Linda D.,Nejo, Adeola A.,Pullabhotla, Viswanadha S.R.,Ndifon, Peter T.,Malik, Mohammad Azad,Akhtar, Javeed,O'Brien, Paul,Revaprasadu, Neerish
, p. 129 - 135 (2014)
We report the synthesis and single X-ray structures of bis(dipiperidinyldithio-carbamato)zinc(II) and bis(ditetrahydroquinolinyldithiocarbamato)zinc(II) complexes. The complexes were thermolysed in hexadecylamine (HDA) and tri-n-octylphosphine oxide (TOPO) at different reaction temperatures to produce HDA and TOPO capped ZnS nanoparticles. The microstructure and morphology of the as-prepared ZnS nanoparticles were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM) and high transmission electron microscopy (HRTEM). Predominantly close to spherical shaped particles were observed in the TEM images of all samples. The optical properties of the particles studied by UV-Vis and photoluminescence (PL) spectroscopy showed evidence of quantum confinement.
Synthesis, Characterization, and Molecular Docking Study of Some Novel Imidazole Derivatives as Potential Antifungal Agents
I??k, Ay?en,Acar ?evik, Ulviye,Sa?l?k, Begüm Nurpelin,?zkay, Yusuf
, p. 142 - 152 (2019/01/04)
The azole pharmacophore is still regarded as a viable lead structure for the synthesis of more effective antifungal agents. In this study, two novel series of imidazole derivatives containing dithiocarbamate (5a–5g) and (benz)azolethiol (6a–6n) side chains that are structurally related to the famous antifungal azole pharmacophore were synthesized, and the structures of them were characterized by spectral (IR, 1H NMR, 13C NMR, and MS spectra) analyses. The synthesized compounds were screened in vitro antifungal activity against pathogenic strains fungi. Theoretical ADME (absorption, distribution, metabolism, and excretion) predictions were calculated for final compounds. A molecular docking study of the most active compound with target “lanosterol 14α-demethylase” (CYP51) was performed to unravel the mode of antifungal action. Compound 5e, which features imidazole and 4-methoxybenzyl piperazine scaffolds, showed the most promising antifungal activity with an MIC50 value of 0.78?μg/mL against C. krusei. Effect of the compound 5e against ergosterol biosynthesis was observed by LC–MS–MS method, which is based on quantification of ergosterol level in C.?krusei.
Design, Synthesis, Molecular Docking, and Cholinesterase Inhibitory Potential of Phthalimide-Dithiocarbamate Hybrids as New Agents for Treatment of Alzheimer's Disease
Asadi, Mehdi,Ebrahimi, Mostafa,Mohammadi-Khanaposhtani, Maryam,Azizian, Homa,Sepehri, Saghi,Nadri, Hamid,Biglar, Mahmood,Amanlou, Massoud,Larijani, Bagher,Mirzazadeh, Roghieh,Edraki, Najmeh,Mahdavi, Mohammad
, (2019/11/11)
A novel series of phthalimide-dithiocarbamate hybrids was synthesized and evaluated for in vitro inhibitory potentials against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). The anti-cholinesterase results indicated that among the synthesized compounds, the compounds 7g and 7h showed the most potent anti-AChE and anti-BuChE activities, respectively. Molecular docking and dynamic studies of the compounds 7g and 7h, respectively, in the active site of AChE and BuChE revealed that these compounds as well interacted with studied cholinesterases. These compounds also possessed drug-like properties and were able to cross the BBB.
