873056-18-9 Usage
Chemical structure
A tetrahydroquinoline core with a spiro linkage and a N'-benzylpiperidine side chain.
Potential pharmaceutical applications
The compound has been studied for its potential use in the treatment of central nervous system disorders.
Dopamine receptor modulator
It has been investigated for its ability to modulate dopamine receptors, which play a crucial role in the regulation of various brain functions.
Central nervous system disorders
The compound may have therapeutic potential in treating conditions such as Parkinson's disease, schizophrenia, and addiction, which are associated with dopamine dysregulation.
Medicinal chemistry
Its unique structure and potential biological activities make it an interesting target for further research and development in the field of medicinal chemistry.
Research focus
The compound's properties and effects on dopamine receptors could lead to the development of new drugs for the treatment of various neurological and psychiatric disorders.
Structure-activity relationship
Understanding the relationship between the compound's structure and its biological activities can help in the design of more potent and selective dopamine receptor modulators.
Synthesis
The synthesis of 1,2,3,4-tetrahydroquinolin-4-spiro-4'-(N'-benzylpiperidine) involves the formation of the tetrahydroquinoline core, the spiro linkage, and the attachment of the N'-benzylpiperidine side chain.
Analytical techniques
Various analytical methods, such as mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and X-ray crystallography, can be used to characterize the compound's structure and confirm its identity.
Safety and toxicity
Further research is needed to evaluate the safety and potential side effects of 1,2,3,4-tetrahydroquinolin-4-spiro-4'-(N'-benzylpiperidine) before it can be considered for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 873056-18-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,3,0,5 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 873056-18:
(8*8)+(7*7)+(6*3)+(5*0)+(4*5)+(3*6)+(2*1)+(1*8)=179
179 % 10 = 9
So 873056-18-9 is a valid CAS Registry Number.
873056-18-9Relevant academic research and scientific papers
Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases
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, (2015/09/22)
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.
SPIRO CONDENSED PIPERIDNES AS MODULATORS OF MUSCARINIC RECEPTORS
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, (2008/06/13)
The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
