87306-63-6

Upstream product

• 57598-33-1 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 594-19-4 tert.-butyl lithium 
• 98-88-4 benzoyl chloride 
• 19312-06-2 4,5-dihydro-4,4-dimethyl-2-phenoxazole 
• 66464-20-8 2-(2-fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 

Downstream Products

• 1077-58-3 2-tert-butylbenzoic acid 
• 16372-51-3 2-tert-butylbenzoyl chloride 
• 16358-79-5 2-tert-butylbenzaldehyde 
• 139287-38-0 2-tert-Butyl-benzoic acid 2-methyl-2-(methyl-trifluoromethanesulfonyl-amino)-propyl ester 
• 87306-67-0 2-(2-tert-Butyl-benzylamino)-2-methyl-propan-1-ol 
• 139287-30-2 2-tert-Butyl-benzoic acid 2-methyl-2-trifluoromethanesulfonylamino-propyl ester 

Relevant academic research and scientific papers

Contra-Friedel-Crafts tert-butylation of substituted aromatic rings via directed metallation and sulfinylation

Directed metallation and sulfinylation yields sulfoxides which undergo ipso nucleophilic aromatic substitution with tertiary and secondary alkyllithiums, giving aromatic rings bearing alkyl groups generally incompatible with directed metallation methods and with regioselectivity complementary with classical Friedel-Crafts substitution. The Royal Society of Chemistry 2006.

Fungicides for the control of take-all disease of plants

A method of controlling Take-All disease of plants by applying a fungicide of the formula STR1 wherein Z1 and Z2 are C and are part of an aromatic ring which is benzothiophene; and A is selected from --C(X)-amine wherein the amine is an unsubstituted, monosubstituted or disubstituted amino radical, --C(O)--SR3, --NH--C(X)R4, and --C(=NR3)--XR7 ; B is --Wm --Q(R2)3 or selected from O-tolyl, 1-naphthyl, 2-naphthyl, and 9-phenanthryl, each optionally substituted with halogen or R4 ; Q is C, Si, Ge, or Sn; W is --C(R3)p H(2-p) --; or when Q is C, W is selected from --C(R3)p H(2-p), --N(R3)m H(1-m)--, --S(O)p--, and --O--; X is 0 or S; n is 0, 1, 2, or 3; m is 0 or 1; p is 0, 1, or 2; each R and R2 is independently defined herein; R3 is C1 -C4 alkyl; R4 is C1 -C4 alkyl, haloalkyl, alkoxy, alkylthio, alkylamino, or dialkylamino; and R7 is C1 -C4 alkyl, haloalkyl, or phenyl, optionally substituted with halo, nitro, or R4 ; or an agronomic salt thereof.

Directed lithiations: The effect of varying directing group orientation on competitive efficiencies for a series of tertiary amide, secondary amide, and alkoxide directed ortho lithiations

Significant differences for competitive efficiencies in directed ortho lithiations for single functional groups in three series, the secondary benzamides 1-4, the tertiary benzamides 5-11, and the benzylic alcohols 12-17, are reported. For both amide seri

A new method for hydrolyzing 2-aryl-4,4-dimethyl-2-oxazolines to aryl carboxylic acids

A method of hydrolyzing 2-aryl-4,4-dimethyl-2-oxazolines with trifluoromethanesulfonic anhydride is described which works well even for highly hindered systems where alternate methods fail.