873426-76-7

Basic information

• Product Name: tert-butyldimethyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)silane
• Synonyms: tert-butyldimethyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)silane
• CAS NO: 873426-76-7
• Molecular Formula: C₁₈H₃₁BO₃Si
• Molecular Weight: 334.33344
• Mol File: 873426-76-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyldimethyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)silane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyldimethyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)silane(873426-76-7)
• EPA Substance Registry System: tert-butyldimethyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)silane(873426-76-7)

Safety Data

• Hazardous Substances Data: 873426-76-7(Hazardous Substances Data)

Upstream product

• 113984-68-2 4-<(dimethyl-tert-butylsilyl)oxy>fluorobenzene 
• 73183-34-3 bis(pinacol)diborane 
• 133430-99-6 4-(tert-butyldimethylsilyloxy)iodobenzene 
• 126644-72-2 1-<(tert-butyldimethylsilyl)oxy>-4-chlorobenzene 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 269409-70-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 159191-56-7 (4-((tert-butyldimethylsilyl)oxy)phenyl)boronic acid 

Downstream Products

• 1334158-57-4 (Z)-3-(4-(tert-butyldimethylsilyloxy)phenyl)-4-(3,5-dimethoxyphenyl)but-3-en-2-ol 
• 1334158-65-4 tert-butyl(4-(5,7-dimethoxy-1-methyl-1H-inden-2-yl)phenoxy)dimethylsilane 
• 1450994-82-7 3-(4-hydroxyphenyl)-2,2-dimethyl-2H-chromen-7-ol 
• 81267-65-4 idronoxil 

Relevant articles and documents

Copper-Photocatalyzed Borylation of Organic Halides under Batch and Continuous-Flow Conditions

The copper-photocatalyzed borylation of aryl, heteroaryl, vinyl and alkyl halides (I and Br) was reported. The reaction proceeded using a new heteroleptic Cu complex under irradiation with blue LEDs, giving the corresponding boronic-acid esters in good to excellent yields. The reaction was extended to continuous-flow conditions to allow an easy scale-up. The mechanism of the reaction was studied and a mechanism based on a reductive quenching (CuI/CuI*/Cu0) was suggested.

Base-Free Palladium-Catalyzed Borylation of Aryl Chlorides with Diborons

The base-free palladium-catalyzed borylation of aryl chlorides with diborons was achieved. The base-free conditions offered acceptable functional group compatibility. Based on experimental and computational studies, it was shown that smooth boryl transfer from the diborons to the arylpalladium chloride was promoted by strong interaction between the Lewis acidic boron and the chlorine atom on palladium.

Total synthesis of eryvarin H and its derivatives and their biological activity as ERRγ inverse agonist

Total synthesis of eryvarin H and a biological investigation of its analogues as a potential inverse agonist of ERRγ are described here. Among the 13 analogues prepared by the modular synthetic route, eryvarin H and compound 12 showed meaningful ERRγ inverse agonistic activities along with moderate selectivity over ERα and other nuclear receptors in the cell-based reporter gene assay.