87343-67-7Relevant academic research and scientific papers
ETUDE DE LA REACTIVE DE COMPOSES ENAMINOCARBONYLES VIS-A-VIS DE LA 1-PHENYLPYRAZOLIDINE-3,5-DIONE
Maquestiau, A.,Eynde, Vanden J. J.
, p. 451 - 458 (2007/10/02)
In acetic acid at room temperature, 3-amino-1-phenyl-2-buten-1-one, 4-amino-3-penten-2-one, various 3-aminocrotonic esters and amides react with 1-phenylpyrazolidin-3,5-dione to yield compounds resulting from the elimination of ammonia between the two precursors and the so obtained derivatives cyclize on heating to pyrano pyrazoles.The rates of these reactions are measured by 1H NMR spectroscopy and mechanistic interpretations are proposed.Under the same experimental conditions, β-dicarbonyl compounds are less reactive than the enaminocarbonyl analogues.
ETUDE COMPARATIVE DE LA REACTIVITE DE L'ACETOACETATE D'ETHYLE ET DU 3-AMINOCROTONATE D'ETHYLE VIS-A-VIS DE COMPOSES PYRAZOLONIQUES
Maquestiau, A.,Haverbeke, Y. van,Eynde, J.-J. Vanden
, p. 451 - 458 (2007/10/02)
1-phenyl-3-methylpyrazolin-5-one, 1,5-dimethylpyrazolin-3-one and 1-phenyl-pyrazolidin-3,5-dione react with ethyl acetoacetate to yield pyrano pyrazole-6-ones.Starting from 1-phenyl-3-aminopyrazolin-5-one or from 1-methyl-5-aminopyrazolin-3-one, pyrazolo pyridin-6-ones are obtained.When ethyl 3-aminocrotonate instead of ethyl acetoacetate is used, the course of these reactions remains the same in most cases but yields are always higher.
