95155-01-4Relevant academic research and scientific papers
ETUDE DE LA REACTIVE DE COMPOSES ENAMINOCARBONYLES VIS-A-VIS DE LA 1-PHENYLPYRAZOLIDINE-3,5-DIONE
Maquestiau, A.,Eynde, Vanden J. J.
, p. 451 - 458 (2007/10/02)
In acetic acid at room temperature, 3-amino-1-phenyl-2-buten-1-one, 4-amino-3-penten-2-one, various 3-aminocrotonic esters and amides react with 1-phenylpyrazolidin-3,5-dione to yield compounds resulting from the elimination of ammonia between the two precursors and the so obtained derivatives cyclize on heating to pyrano pyrazoles.The rates of these reactions are measured by 1H NMR spectroscopy and mechanistic interpretations are proposed.Under the same experimental conditions, β-dicarbonyl compounds are less reactive than the enaminocarbonyl analogues.
