87344-05-6 Usage
Uses
Used in Pharmaceutical Industry:
Tolmetin glycinamide is used as an anti-inflammatory and analgesic agent for the treatment of conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Its conversion to tolmetin allows for effective management of pain and inflammation associated with these conditions.
Used in Pain Management:
Tolmetin glycinamide serves as a pain reliever, particularly for individuals suffering from mild to moderate pain due to inflammatory conditions. Its action in reducing prostaglandin production helps alleviate discomfort and promote healing.
Used in Fever Reduction:
As a fever-reducing agent, tolmetin glycinamide is utilized to lower elevated body temperatures caused by inflammation or other underlying conditions, providing relief and supporting the body's recovery process.
Check Digit Verification of cas no
The CAS Registry Mumber 87344-05-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,3,4 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 87344-05:
(7*8)+(6*7)+(5*3)+(4*4)+(3*4)+(2*0)+(1*5)=146
146 % 10 = 6
So 87344-05-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H18N2O4/c1-11-3-5-12(6-4-11)17(23)14-8-7-13(19(14)2)9-15(20)18-10-16(21)22/h3-8H,9-10H2,1-2H3,(H,18,20)(H,21,22)
87344-05-6Relevant academic research and scientific papers
Synthesis and process optimization of amtolmetin: An antiinflammatory agent
Reddy, Lekkala Amarnath,Chakraborty, Saurya,Swapna, Rodda,Bhalerao, Dinesh,Malakondaiah, Golla China,Ravikumar, Mylavarapu,Kumar, Abhijeet,Reddy, Gade Srinivas,Naram, Jyothirmayi,Dwivedi, Namrata,Roy, Arnab,Himabindu, Vurimidi,Babu, Bangaru,Bhattacharya, Apurba,Bandichhor, Rakeshwar
, p. 362 - 368 (2011/03/21)
Efforts toward the synthesis and process optimization of amtolmetin guacil 1 are described. High-yielding electrophilic substitution followed by Wolf-Kishner reduction are the key features in the novel synthesis of tolmetin 2 which is an advanced intermediate of 1.
