87356-72-7Relevant academic research and scientific papers
The ruthenium-catalyzed C-H functionalization of enamides with isocyanates: Easy entry to pyrimidin-4-ones
Shi, Pengfei,Li, Song,Hu, Lu-Min,Wang, Cong,Loh, Teck-Peng,Hu, Xu-Hong
, p. 11115 - 11118 (2019)
Ruthenium-catalyzed heteroannulation between enamides and isocyanates has been realized as a complementary approach to conventional strategies for the synthesis of pyrimidin-4-ones. High step-A nd atom-economy was achieved for the rapid construction of such privileged scaffolds, which are found in a multitude of pharmaceutical compounds. The generality and practicability of this transformation were reflected by the broad scope of substrates with diverse functional groups, large-scale synthesis, and late-stage diversification.
A multi-substituted pyrimidine compound and its preparation method
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Paragraph 0030-0033, (2019/07/08)
The present invention discloses a multi-substituted pyrimidine compounds, its structure is shown as formula shown to: Its preparation method is as follows: under the protection of nitrogen, to the Schlenk reaction tube are separately adding substitution e
Synthesis and Biological Evaluation of 6-Substituted 3-Aryl-2-methyl-4(3H)-pyrimidones
Gupta, K. A.,Saxena, Anil K.,Jain, Padam C.,Srimal, R. C.,Kar, K.,Anand, Nitya
, p. 384 - 387 (2007/10/02)
6-Substituted 3-aryl-2-methyl-4(3H)-pyrimidones (III) have been prepared by the reaction of N-arylacetamidines (II) with various diplorophiles like ethyl propiolate, ethyl tetrolate and ethyl phenylpropiolate.The structure of the products has been confirm
