873695-06-8

Upstream product

• 338463-00-6 N-(tert-butoxycarbonyl)-N-but-3-ynyl-4-methylbenzenesulfonamide 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 873695-05-7 tert-butyl (4-bromobut-3-yn-1-yl)(tosyl)carbamate 

Downstream Products

• 873694-88-3 N-(4-bromobut-3-ynyl)-N-hexa-2,4-dienyl-4-methylbenzenesulfonamide 
• 1607830-06-7 N-(3-bromobut-3-en-1-yl)-4-methyl-N-(4-(4-methyl-N-(oct-1-yn-1-yl)phenylsulfonamido)but-1-yn-1-yl)benzenesulfonamide 
• 1607830-18-1 C₁₉H₂₄BrNO₂S 

Relevant academic research and scientific papers

Palladium-catalyzed cyclization of bromoenynamides to tricyclic azacycles: Synthesis of trikentrin-like frameworks

Palladium-catalyzed cascade cyclization of bromoenynamides equipped with an additional alkyne or ynamide substituent affords azatricyclic products. Using 5- to 7-membered ring tethers, this chemistry offers a regiospecific route to highly-functionalized azacycles. Elaboration to the trikentrin B skeleton is achieved from the arylsilane cyclization products. the Partner Organisations 2014.

Rhodium-catalyzed intramolecular [4 + 2] cycloadditions of alkynyl halides

(Chemical Equation Presented) Cationic rhodium(I)-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were found to occur in good yields (70-87%). The halide moiety is compatible with the cycloaddition reactions, and no oxidative insertion to the alkynyl halide was observed. The halogen-containing cycloadducts could be transformed into a variety of products that are difficult or impossible to obtain via direct cycloaddition.