873695-38-6Relevant academic research and scientific papers
NHC ligand-enabled Ni-catalyzed reductive coupling of alkynes and imines using isopropanol as a reductant
Yao, Wei-Wei,Li, Ran,Li, Jiang-Fei,Sun, Juan,Ye, Mengchun
supporting information, p. 2240 - 2244 (2019/05/17)
A nickel-catalyzed reductive coupling of alkynes and imines using readily available isopropanol as the reducing agent was developed. The use of a sterically bulky and electron-rich carbene ligand (AnIPr) significantly promotes the reaction, providing various multi-substituted allylic amines in 23-89% yield and the corresponding chiral ligand (AnIPr-3) can afford the products in 51-95% ee.
A General Asymmetric Formal Synthesis of Aza-Baylis–Hillman Type Products under Bifunctional Catalysis
Frías, María,Carrasco, Ana Cristina,Fraile, Alberto,Alemán, José
supporting information, p. 3117 - 3121 (2017/12/26)
A new organocatalytic strategy for the synthesis of enantioenriched aza-Baylis–Hillman type products via a frustrated vinylogous reaction is presented. This process proceeds under mild conditions with good yields, completed Z/E selectivity and excellent e
Chemoselective Boron-Catalyzed Nucleophilic Activation of Carboxylic Acids for Mannich-Type Reactions
Morita, Yuya,Yamamoto, Tomohiro,Nagai, Hideoki,Shimizu, Yohei,Kanai, Motomu
supporting information, p. 7075 - 7078 (2015/06/25)
The carboxyl group (COOH) is an omnipresent functional group in organic molecules, and its direct catalytic activation represents an attractive synthetic method. Herein, we describe the first example of a direct catalytic nucleophilic activation of carbox
A facile synthesis of N-sulfonyl and N-sulfinyl aldimines under Barbier-type conditions
Fan, Renhua,Pu, Dongming,Wen, Fengqi,Ye, Yang,Wang, Xiaoli
, p. 3623 - 3625 (2008/09/20)
(Chemical Equation Presented) A convenient synthesis of N-sulfonyl- and N-sulfinylimines by the condensation of aldehydes with sulfonyl or sulfinyl amides in the presence of benzyl bromide and zinc dust at room temperature under the Barbier-type condition
A general method for the preparation of N-sulfonyl aldimines and ketimines
García Ruano, José Luis,Alemán, José,Cid, M. Belén,Parra, Alejandro
, p. 179 - 182 (2007/10/03)
(Chemical Equation Presented) A simple procedure to obtain N-sulfonyl imines involving the condensation of carbonyl compounds with p-tolyl or tert-butyl sulfinamides followed by oxidation with m-CPBA of the resulting N-sulfinylimines is reported. The meth
A new general method for the preparation of N-sulfonyloxaziridines
Garcia Ruano, Jose Luis,Aleman, Jose,Fajardo, Cristina,Parra, Alejandro
, p. 5493 - 5496 (2007/10/03)
(Chemical Equation Presented) A simple procedure to obtain N-alkylsulfonyl- and N-arylsulfonyloxaziridines from the corresponding N-sulfinylimines involving a one-pot, two-step oxidation process with m-CPBA (1 equiv) and m-CPBA/KOH (1.1 equiv) is reported
