873790-27-3Relevant articles and documents
Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors
De, Surya K.,Chen, Vida,Stebbins, John L.,Chen, Li-Hsing,Cellitti, Jason F.,Machleidt, Thomas,Barile, Elisa,Riel-Mehan, Megan,Dahl, Russell,Yang, Li,Emdadi, Aras,Murphy, Ria,Pellecchia, Maurizio
scheme or table, p. 590 - 596 (2010/05/02)
A series of thiadiazole derivatives has been designed as potential allosteric, substrate competitive inhibitors of the protein kinase JNK. We report on the synthesis, characterization and evaluation of a series of compounds that resulted in the identifica
