874-43-1

Basic information

• Product Name: 5-aminomethyl-2-methylpyrimidin-4-ylamine dihydrochloride
• Synonyms: 5-aminomethyl-2-methylpyrimidin-4-ylamine dihydrochloride;Einecs 212-862-7;5-(Aminomethyl)-2-methylpyrimidin-4-amine dihydrochloride;-2-methylpyrimidin-4-amine dihydrochloride
• CAS NO: 874-43-1
• Molecular Formula: C₆H₁₀N₄*2ClH
• Molecular Weight: 211.09228
• EINECS: 212-862-7
• Product Categories: Bases & Related Reagents Related Reagents;Amines;Aromatics;Enzyme substrates;Heterocycles;Nucleotides
• Mol File: 874-43-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 270-272°C
• Boiling Point: 301.6 °C at 760 mmHg
• Flash Point: 161.5 °C
• Appearance: /
• Vapor Pressure: 0.00104mmHg at 25°C
• Storage Temp.: -20°C Freezer
• CAS DataBase Reference: 5-aminomethyl-2-methylpyrimidin-4-ylamine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-aminomethyl-2-methylpyrimidin-4-ylamine dihydrochloride(874-43-1)
• EPA Substance Registry System: 5-aminomethyl-2-methylpyrimidin-4-ylamine dihydrochloride(874-43-1)

Safety Data

• Hazardous Substances Data: 874-43-1(Hazardous Substances Data)

Usage

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Substrate for TenA enzyme in the thiamin salvage pathway

InChI:InChI=1/C6H10N4.2ClH/c1-4-9-3-5(2-7)6(8)10-4;;/h3H,2,7H2,1H3,(H2,8,9,10);2*1H

Upstream product

• 32795-64-5 5-(2-hydroxy-ethyl)-4-methyl-3H-thiazol-2-one 
• 2421-50-3 N-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-N-(4-hydroxy-1-methyl-2-thiocyanato-but-1-en-t-yl)-formamide 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 

Downstream Products

• 73-66-5 5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine 
• 66840-33-3 7-methyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one 
• 7403-34-1 7-methyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidine-2-thione 
• 490-82-4 thiamine thiazolone 
• 109039-39-6 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-phenyl-3H-thiazole-2-thione 
• 1246636-78-1 methyl 2-(4-(6-((4-amino-2-methylpyrimidin-5-yl)methylamino)pyrimidin-4-yloxy)phenyl)acetate 
• 1344707-26-1 (R/S)-N-((4-amino-2-methylpyrimidin-5-yl)methyl)-2-hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)acetamide 
• 109653-94-3 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-phenyl-thiazolium; chloride-hydrochloride 
• 92-35-3 thiochrome 
• 25526-81-2 5-bromomethyl-2-methyl-pyrimidin-4-ylamine 

Relevant articles and documents

2-Alkyl-4-amino-5-aminomethylpyrimidines

A novel 2-lower alkyl-4-amino-5-substituted iminopyrimidine compound represented by the formula: STR1 wherein R is a lower alkyl, and Y is hydroxyl or amino which may be protected or a salt thereof is obtainable by allowing a formylpyrimidine compound represented by the formula: STR2 wherein R is a lower alkyl to react with a compound represented by the formula H2 N--Y, wherein Y is hydroxyl or amino which may be protected, or a salts thereof. The iminopyrimidine compound gives the known pyrimidine compound represented by the formula: STR3 wherein R is as defined above in high yield. Therefor, the process is very useful as an industrial production method.