87401-27-2 Usage
General Description
1-(2,6-dibromo-1-methyl-1H-indol-3-yl)-N,N-dimethylmethanamine hydrobromide is a chemical compound that consists of a hydrobromide salt of a dimethylmethanamine molecule attached to a 2,6-dibromo-1-methyl-1H-indol-3-yl group. It is a derivative of indole, a heterocyclic aromatic compound that is widely distributed in nature and is a precursor to many important natural products. This particular chemical compound may have potential applications in the field of medicinal chemistry, particularly in the development of novel pharmaceutical drugs that target specific biological pathways. However, given its complex structure and potential reactivity, it should be handled and used with caution, following proper safety protocols and guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 87401-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,4,0 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 87401-27:
(7*8)+(6*7)+(5*4)+(4*0)+(3*1)+(2*2)+(1*7)=132
132 % 10 = 2
So 87401-27-2 is a valid CAS Registry Number.
87401-27-2Relevant articles and documents
Bromoderivatives of gramines. Preparation and pharmacological properties
Franzone, Jose Sebastian,Cirillo, Rocco,Cravanzola, Carlo
, p. 261 - 268 (2007/10/02)
Bromination of gramine (I), 1-methylgramine (IX), 2-methylgramine (IV) and 1,2-dimethylgramine (XV) with different mole ratios of bromine to substrate was investigated; it was seen that the 5- and 6-position are the normal sites of bromination and 1-methylgramines (IX) and (XV) give better yields of bromoderivatives.Among the compounds submitted the pharmacological screening, 2,6-dibromo-1-methylgramine hydrobromide (Xa) and especially 6-bromo-2-methylgramine (V) showed a clear antiserotoninic antiinflammatory and analgesic activity.Furthermore gramine (V) showed a good anti prostaglandin synthetase activity in vitro.Key-words: Bromogramines. - Antiserotonic activity. - Antiinflammatory activity.
