87412-86-0 Usage
Uses
Used in Pharmaceutical Industry:
1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one is used as a glycogen phosphorylase inhibitor for the potential treatment of type 2 diabetes and other metabolic disorders. Its ability to inhibit glycogen phosphorylase may help regulate glucose metabolism and improve insulin sensitivity, offering a potential therapeutic approach for managing these conditions.
Additionally, due to its unique structure and properties, 1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one is used as a candidate for further drug development and research in the field of medicinal chemistry. This allows for the exploration of its potential applications in various therapeutic areas and the development of new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 87412-86-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,4,1 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 87412-86:
(7*8)+(6*7)+(5*4)+(4*1)+(3*2)+(2*8)+(1*6)=150
150 % 10 = 0
So 87412-86-0 is a valid CAS Registry Number.
87412-86-0Relevant academic research and scientific papers
Aryl Coupling Reactions of Pyrazolopyrimidin-4-yl Radicals
Press, Jeffery B.,Eudy, Nancy H.,Morton, George O.
, p. 4605 - 4611 (2007/10/02)
4-Arylpyrazolopyrimidines (4) were the subjects of a synthetic investigation in order to evaluate their biological activity.Attempts to prepare 4 from 4-aminopyrazolopyrimidines (5) via classical Gomberg-Bachmann-Hey aryl coupling conditions failed.Conversion of 5 to 4 was accomplished by diazotiazation of 5 using alkyl nitrites with an acid catalyst in aromatic solvents.Isomer distribution of the aryl-coupled products 4 was that predicted for a radical intermediate (ortho > meta ca. para); isomer structures were assigned by a detailed 1H NMR analysis.Unusual fragmentation products 17 and 18 were isolated during the course of investigations.These oxadiazoles probably arise from collapse of intermediate pyrazolopyrimidin-4-yl radicals 15.
