874141-25-0Relevant academic research and scientific papers
Efficient synthesis of β'-amino-α, β-unsaturated ketones
Abrunhosa-Thomas, Isabelle,Plas, Aurelie,Kandepedu, Nishanth,Chalard, Pierre,Troin, Yves
, p. 486 - 495 (2013/04/23)
A general and simple procedure to access chiral β'-amino-α, β-enones, in seven steps, from an α,β unsaturated ester has been described. The use of a Horner-Wadsworth-Emmons reaction as a key step for generating the β'-amino-α,β-enones, permits access to a range of substrates under mild conditions and in moderate to high yield.
Asymmetric synthesis of 1,3-aminoketals
Bariau, Annabelle,Canet, Jean-Louis,Chalard, Pierre,Troin, Yves
, p. 3650 - 3660 (2007/10/03)
The asymmetric synthesis of α-chiral 1,3-aminoketals 1, useful chiral building blocks for piperidine preparation, was achieved in seven steps involving highly diastereoselective 1,4-addition of Davies' lithium amide to an α,β-unsaturated ester. Problems o
