87418-76-6Relevant academic research and scientific papers
Synthesis and biological evaluation of novel selenonucleosides
Chen, Yao,Peng, Yingdan,Zhang, Jiancun,Fu, Lei
, p. 1001 - 1008 (2008/12/22)
A series of novel selenonucleoside analogues with 1,4-oxaselenane as the carbohydrate fragment has been synthesized from their corresponding dimesylated seconucleosides treated with NaHSe solution and subsequent deprotection. The synthesized selenonucleos
Phosphoramidate dinucleosides as hepatitis C virus polymerase inhibitors
Zlatev, Ivan,Dutartre, Hélène,Barvik, Ivan,Neyts, Johan,Canard, Bruno,Vasseur, Jean-Jacques,Alvarez, Karine,Morvan, Fran?ois
supporting information; experimental part, p. 5745 - 5757 (2009/09/29)
GC dinucleosides exhibiting a phosphoramidate internucleosidic linkage with neutral, amphiphile, positively or negatively charged side chains were synthesized. Their potential inhibitory effect on the hepatitis C virus (HCV) NS5B polymerase was evaluated
Antisense modulation of CDC14A expression
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Page/Page column 16, (2010/02/06)
Antisense compounds, compositions and methods are provided for modulating the expression of CDC14A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CDC14A. Methods of using these compounds for modulation of CDC14A expression and for treatment of diseases associated with expression of CDC14A are provided.
The preparation of protected arabinonucleosides
Ogilvie, Kelvin K.,McGee, Danny P. C.,Boisvert, Suzanne M.,Hakimelahi, Gholam H.,Proba, Zbigniew A.
, p. 1204 - 1212 (2007/10/02)
A general procedure is described for the preparation of protected arabinonucleosides.Protection at the 5'-position involves triphenylmethyl groups (DMT and MMT) while the tert-butyldimethylsilyl (TBDMS) group is used to protect the 2'- or 3'-positions.The
New catalists and procedures for the dimethoxytritylation and selective silylation of ribonucleosides
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 1106 - 1113 (2007/10/02)
Procedures have been developed for the selective formation of (a) 2',5'-silylated ribonucleosides and (b) 3',5'-silylated ribonucleosides.These procedures also permit the selective silylation at either the 2'- or 3'-position of dimethoxytritylated ribonuc
