87424-98-4

Basic information

• Product Name: 2-BROMOPHENYL ETHYL SULFIDE
• Synonyms: 2-BROMOPHENYL ETHYL SULFIDE;2-Bromophenylethylsulphide;2-bromophenyl ethyl;1-bromo-2-(ethylsulfanyl)benzene;(2-bromophenyl)(ethyl)sulfane
• CAS NO: 87424-98-4
• Molecular Formula: C₈H₉BrS
• Molecular Weight: 217.13
• Mol File: 87424-98-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 248.041 °C at 760 mmHg
• Flash Point: 103.812 °C
• Appearance: /
• Density: 1.448 g/cm³
• Vapor Pressure: 0.039mmHg at 25°C
• Refractive Index: 1.607
• CAS DataBase Reference: 2-BROMOPHENYL ETHYL SULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOPHENYL ETHYL SULFIDE(87424-98-4)
• EPA Substance Registry System: 2-BROMOPHENYL ETHYL SULFIDE(87424-98-4)

Safety Data

• Hazardous Substances Data: 87424-98-4(Hazardous Substances Data)

Usage

General Description

2-Bromophenyl Ethyl Sulfide is a chemical compound with the formula C8H9BrS. It is a brominated organic compound containing a sulfide functional group. This chemical is commonly used in organic synthesis as a building block for creating other organic compounds. It is also used as a reagent in chemical reactions and pharmaceutical research. 2-Bromophenyl Ethyl Sulfide has a variety of applications in the fields of pharmaceuticals, agrochemicals, and material science due to its versatile chemical properties and reactivity. It is important to handle this chemical with caution and use appropriate safety measures as it may pose health hazards if not properly managed.

InChI:InChI=1/C8H9BrS/c1-2-10-8-6-4-3-5-7(8)9/h3-6H,2H2,1H3

Upstream product

• 13920-91-7 2-(ethylthio)aniline 
• 3058-46-6 1-ethylsulfanyl-2-nitrobenzene 
• 75-03-6 ethyl iodide 
• 6320-02-1 o-bromothiophenol 
• 1072-85-1 o-fluorobromobenzene 
• 75-08-1 ethanethiol 

Downstream Products

• 362045-33-8 [2-(ethylsulphanyl)phenyl]boronic acid 
• 112921-53-6 ethyl (2-bromo)phenyl sulfoxide 
• 1299474-17-1 1-bromo-2-(ethylsulfonyl)benzene 

Relevant articles and documents

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.

Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis

Palmitoylethanolamide (PEA) and oleoylethanolamide (OEA) are endogenous lipid mediators that suppress inflammation. Their actions are terminated by the intracellular cysteine amidase, N-acylethanolamine acid amidase (NAAA). Even though NAAA may offer a new target for anti-inflammatory therapy, the lipid-like structures and reactive warheads of current NAAA inhibitors limit the use of these agents as oral drugs. A series of novel benzothiazole–piperazine derivatives that inhibit NAAA in a potent and selective manner by a non-covalent mechanism are described. A prototype member of this class (8) displays high oral bioavailability, access to the central nervous system (CNS), and strong activity in a mouse model of multiple sclerosis (MS). This compound exemplifies a second generation of non-covalent NAAA inhibitors that may be useful in the treatment of MS and other chronic CNS disorders.

PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS

The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.