87424-98-4

Usage

Uses

Used in Organic Synthesis:
2-Bromophenyl Ethyl Sulfide is utilized as a key building block in the synthesis of various organic compounds. Its presence in the molecular structure allows for the formation of a wide range of derivatives, contributing to the development of new chemical entities with potential applications across different industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-Bromophenyl Ethyl Sulfide is employed as a reagent in chemical reactions aimed at discovering and developing new drugs. Its versatile chemical properties and reactivity make it a valuable tool in medicinal chemistry for the synthesis of bioactive molecules and potential therapeutic agents.
Used in Agrochemicals:
2-Bromophenyl Ethyl Sulfide finds applications in the agrochemical sector, where it is used in the synthesis of various agrochemical products. Its chemical properties allow it to be a component in the development of pesticides, herbicides, and other agricultural chemicals that are essential for crop protection and yield enhancement.
Used in Material Science:
In the field of material science, 2-Bromophenyl Ethyl Sulfide is used to develop new materials with specific properties. Its reactivity and ability to form various chemical bonds make it a candidate for the creation of materials with tailored characteristics for use in different applications, such as in polymers, coatings, and advanced materials.
Safety Considerations:
Given the potential health hazards associated with 2-Bromophenyl Ethyl Sulfide, it is crucial to handle this chemical with care and implement appropriate safety measures during its use. This includes the use of personal protective equipment, proper storage, and adherence to safety protocols to minimize risks to human health and the environment.

InChI:InChI=1/C8H9BrS/c1-2-10-8-6-4-3-5-7(8)9/h3-6H,2H2,1H3

Upstream product

• 75-03-6 ethyl iodide 
• 6320-02-1 o-bromothiophenol 
• 1072-85-1 o-fluorobromobenzene 
• 75-08-1 ethanethiol 
• 3058-46-6 1-ethylsulfanyl-2-nitrobenzene 
• 13920-91-7 2-(ethylthio)aniline 

Downstream Products

• 362045-33-8 [2-(ethylsulphanyl)phenyl]boronic acid 
• 1299474-17-1 1-bromo-2-(ethylsulfonyl)benzene 
• 112921-53-6 ethyl (2-bromo)phenyl sulfoxide 

Relevant academic research and scientific papers

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.

Dibenzofuran heptabasic condensed ring unit and derivative, preparation method and application thereof

The invention belongs to the technical field of organic optoelectronics, and discloses a dibenzofuran heptabasic condensed ring unit and a derivative, a preparation method and application thereof. Thechemical structural formula of the dibenzofuran heptabasic condensed ring unit is shown in general formula as shown in specification, in the formula, R1 is C1-30 alkyls, C3-30 cycloalkyls, C6-60 aromatic hydrocarbyls or C3-60 aromatic heterocyclyls; X is -C(R2)2-, -NR2-, -Si(R2)2-, -O-, -S-, -SO2- or -CO2-; and R2 is C1-30 alkyls, C3-30 cycloalkyls, C6-60 aromatic hydrocarbyls or C3-60 aromatic heterocyclyls. The invention further provides a derivative based on the dibenzofuran heptabasic condensed ring unit. The dibenzofuran heptabasic condensed ring and the derivative thereof effectively improve the fluorescence quantum yield and thermal stability, and a hole transfer property, and can be applied to preparation of an organic light-emitting diode light-emitting layer.

Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis

Palmitoylethanolamide (PEA) and oleoylethanolamide (OEA) are endogenous lipid mediators that suppress inflammation. Their actions are terminated by the intracellular cysteine amidase, N-acylethanolamine acid amidase (NAAA). Even though NAAA may offer a new target for anti-inflammatory therapy, the lipid-like structures and reactive warheads of current NAAA inhibitors limit the use of these agents as oral drugs. A series of novel benzothiazole–piperazine derivatives that inhibit NAAA in a potent and selective manner by a non-covalent mechanism are described. A prototype member of this class (8) displays high oral bioavailability, access to the central nervous system (CNS), and strong activity in a mouse model of multiple sclerosis (MS). This compound exemplifies a second generation of non-covalent NAAA inhibitors that may be useful in the treatment of MS and other chronic CNS disorders.

2- [1-PHENYL-5-HYDROXY-4a-SUBSTITUTED-HEXAHYDROCYCLOPENTA [F] INDAZOL-5-YL] ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS

The present invention encompasses compounds of Formula I: or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions.

PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS

The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.

Furanyl, tetracyclic triterpene derivatives with immunosuppressant activity

The compounds of Formula I are useful as immunosuppressive agents.

Tetracyclic triterpene derivatives with immunosuppressant activity

The compounds of Formula I are useful as immunosuppressive agents.