874306-27-1

Upstream product

• 434-13-9 Lithocholic acid 
• 591-20-8 3-Bromophenol 
• 20414-15-7 5β-cholane-3α,24-diol 

Downstream Products

• 874306-28-2 (3α,5β)-3,24-bis(3-bromophenoxy)cholane 
• 874306-45-3 N-(3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}propyl)-3-([(3β,5β,17α,20S)-24-{3-[(3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}propyl)amino]phenoxy}cholan-3-yl]oxy)aniline 
• 874306-46-4 N¹-[3-((R)-4-{(3S,5R,8R,9S,10S,13R,14S,17R)-3-[3-(3-Amino-propylamino)-phenoxy]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentyloxy)-phenyl]-propane-1,3-diamine 

Relevant academic research and scientific papers

Synthesis of nitrogen- and oxygen-containing macrocycles - Derivatives of lithocholic acid

Palladium-catalyzed amination of 3,24-bis(3-bromophenoxy)cholane (4) with various polyamines and polyoxadiamines 5 taken in 1:1 ratio was used for the synthesis of the macrocycles 6, which contain steroidal and polyamine moieties and were obtained in 38-6