874306-45-3Relevant academic research and scientific papers
Palladium-catalyzed amination in the synthesis and modification of acyclic oxadiamino cholane derivatives
Ranyuk,Averin,Lukashev,Buryak,Beletskaya
experimental part, p. 1755 - 1768 (2010/05/19)
Palladium-catalyzed reactions of 24-(haloaryloxy)cholanes and 3,24-bis(haloaryloxy)cholanes with excess oxadiamines gave the corresponding mono- and bis(oxadiamino)-substituted cholanes which were subjected to palladium-catalyzed arylation with 1,3-dibrom
Cross-coupling reactions for steroid modification: From arylation to macrocycle syntheses
Lukashev, Nikolay V.,Averin, Alexei D.,Latyshev, Gennadij V.,Donez, Pavel A.,Ranyuk, Elena R.,Beletskaya, Irina P.
, p. 559 - 572 (2007/10/03)
The Suzuki-Miyaura coupling of 4- and 6-halosteroids affords good to excellent yields of potential aromatase inhibitors. While the reaction with 4- and 6-bromo derivatives is catalyzed by Pd(PPh3)2Cl2, the coupling with 6-
Synthesis of nitrogen- and oxygen-containing macrocycles - Derivatives of lithocholic acid
Averin, Alexei D.,Ranyuk, Elena R.,Lukashev, Nikolai V.,Beletskaya, Irina P.
, p. 7030 - 7039 (2007/10/03)
Palladium-catalyzed amination of 3,24-bis(3-bromophenoxy)cholane (4) with various polyamines and polyoxadiamines 5 taken in 1:1 ratio was used for the synthesis of the macrocycles 6, which contain steroidal and polyamine moieties and were obtained in 38-6
