874476-55-8 Usage
Uses
Used in Organic Synthesis:
Tert-Butyl [5-(hydroxymethyl)pyrazin-2-yl]carbamate is used as a reagent in organic synthesis for its ability to facilitate the formation of complex organic molecules. Its unique structure allows it to participate in various chemical reactions, making it a valuable component in the synthesis of pharmaceuticals and other organic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, tert-Butyl [5-(hydroxymethyl)pyrazin-2-yl]carbamate is utilized as a starting material or intermediate in the development of new drugs. Its structural features enable it to be modified and optimized for specific therapeutic targets, contributing to the advancement of novel pharmaceutical agents.
Used in Insecticide Development:
Tert-Butyl [5-(hydroxymethyl)pyrazin-2-yl]carbamate is studied for its potential as an insecticide, leveraging its chemical properties to control or eliminate insect pests. Its effectiveness in this application is under investigation, with the aim of developing safer and more environmentally friendly insect control solutions.
Used in Treatment of Parasitic Infections:
tert-Butyl [5-(hydroxymethyl)pyrazin-2-yl]carbamate is also being explored for its potential use in treating parasitic infections. Its unique chemical structure may offer new avenues for combating parasitic diseases, providing a basis for the development of new therapeutic agents.
Used in Drug Development for Medical Conditions:
Tert-Butyl [5-(hydroxymethyl)pyrazin-2-yl]carbamate is under investigation for its potential role in the development of new drugs for a variety of medical conditions. Its versatility and chemical properties make it a promising candidate for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 874476-55-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,4,7 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 874476-55:
(8*8)+(7*7)+(6*4)+(5*4)+(4*7)+(3*6)+(2*5)+(1*5)=218
218 % 10 = 8
So 874476-55-8 is a valid CAS Registry Number.
874476-55-8Relevant academic research and scientific papers
SELECTIVE INHIBITORS AGAINST Cdk4 AND Cdk6 HAVING AMINOTHIAZOLE SKELETON
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Page/Page column 33, (2010/11/25)
The present invention relates to a compound represented by Formula [I]: wherein X is O, S, NH or CH 2 ; Y 1 , Y 2 , Y 3 , Y 4 and Y 5 , which may be identical or different, are each CH or N; however, at least one of Y 1 , Y 2 , Y 3 , Y 4 and Y 5 is N; Z 1 and Z 2 , which may be identical or different, are each CH or N; n is an integer from 1 to 3; R 1 is a C 3 -C 8 cycloalkyl group, a C 6 -C 10 aryl group, an aliphatic heterocyclic ring or an aromatic heterocyclic ring, or a bicyclic aliphatic saturated hydrocarbon group; R 2 and R 3 , which may be identical or different, are each a hydrogen atom, a lower alkyl group, a lower alkenyl group, a C 3 -C 8 cycloalkyl group, a C 6 -C 10 aryl group, an aromatic heterocyclic ring, or the like; and R 4 is a hydrogen atom, a lower alkyl group, a C 3 -C 6 cycloalkyl group or the like, or a pharmaceutically acceptable salt or ester thereof, and a selective inhibitor against Cdk4 and/or Cdk6 or an anticancer agent containing the compound or a pharmaceutically acceptable salt or ester thereof.
Identification of potent 5-pyrimidinyl-2-aminothiazole CDK4, 6 inhibitors with significant selectivity over CDK1, 2, 5, 7, and 9
Shimamura, Tadashi,Shibata, Jun,Kurihara, Hideki,Mita, Takashi,Otsuki, Sachie,Sagara, Takeshi,Hirai, Hiroshi,Iwasawa, Yoshikazu
, p. 3751 - 3754 (2007/10/03)
5-Pyrimidinyl-2-aminothiazole 1 was identified as an inhibitor of cyclin-dependent kinases (CDKs) by a screening of the Merck sample repository. The introduction of a methyl group at the C-5 or C-6 position on the pyrimidine ring, directed toward the gate
