874480-23-6

Basic information

• Product Name: Zinc, bis(2-nitrophenyl)-
• CAS NO: 874480-23-6
• Molecular Formula: C12H8N2O4Zn
• Molecular Weight: 309.597
• Mol File: 874480-23-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Zinc, bis(2-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, bis(2-nitrophenyl)-(874480-23-6)
• EPA Substance Registry System: Zinc, bis(2-nitrophenyl)-(874480-23-6)

Safety Data

• Hazardous Substances Data: 874480-23-6(Hazardous Substances Data)

Upstream product

• 609-73-4 o-nitroiodobenzene 
• 7646-85-7 zinc(II) chloride 
• 577-19-5 2-nitrophenyl bromide 

Downstream Products

• 151510-31-5 N-(2-nitrophenyl)dibenzylamine 
• 5320-98-9 N-(2-nitrophenyl)morpholine 

Relevant articles and documents

Synthesis of Polyfunctional Diorganomagnesium and Diorganozinc Reagents through In Situ Trapping Halogen–Lithium Exchange of Highly Functionalized (Hetero)aryl Halides in Continuous Flow

We report a halogen–lithium exchange performed in the presence of various metal salts (ZnCl2, MgCl2?LiCl) on a broad range of sensitive bromo- or iodo(hetero)arenes using BuLi or PhLi as the exchange reagent and a commercially available continuous-flow setup. The resulting diarylmagnesium or diarylzinc species were trapped with various electrophiles, resulting in the formation of polyfunctional (hetero)arenes in high yields. This method enables the functionalization of (hetero)arenes containing highly sensitive groups such as an isothiocyanate, nitro, azide, or ester. A straightforward scale-up was possible without further optimization.