87513-48-2Relevant academic research and scientific papers
Steric and Electronic Control of the Dissociative Hydrolysis of 4-Hydoxybenzoate Esters
Thea, Sergio,Guanti, Giuseppe,Kashefi-Naini, Nasrin,Williams, Andrew
, p. 529 - 530 (2007/10/02)
The introduction of two ortho methyl substituents changes the propensity of 4-hydroxybenzoates to react via the oxo-ketene pathway by nearly one million-fold; the increased reactivity of the hindered conjugate base over that of the parent is assigned to enhanced internal nucleophilicity of the 4-oxyanion.
