875210-92-7Relevant academic research and scientific papers
A novel class of potent nonglycosidic and nonpeptidic pan-selectin inhibitors
Ulbrich, Holger K.,Luxenburger, Andreas,Prech, Philip,Eriksson, Einar E.,Soehnlein, Oliver,Rotzius, Pierre,Lindbom, Lennart,Dannhardt, Gerd
, p. 5988 - 5999 (2007/10/03)
An early step of the inflammatory response, the rolling of leukocytes on activated endothelial cells, is mediated by selectin/carbohydrate interactions. The tetrasaccharide sialy LewisX is a ligand for E-, P-, and L-selectin and therefore serve
NON-GLYCOSIDIC AND NON-PEPTIDIC SELECT INHIBITORS, AND THE USE THEREOF
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Page/Page column 29-30, (2008/06/13)
The invention relates to a category of non-glycosidic and non-peptidic select inhibitors of general formula (1), with a low molecular weight, and to a method for the production thereof. Said category is a category of non-toxic select inhibitors having an
