875222-22-3Relevant academic research and scientific papers
Highly efficient preparation of both enantiomers of versatile chiral synthon for 1,2-diamines via the Fe(III)-catalyzed oxidation of 2-imidazolone
Matsunaga, Hirofumi,Eshita, Iori,Tsunoda, Shoichi,Ishimoto, Naoko,Ando, Shin,Ishizuka, Tadao
, p. 1337 - 1353 (2014)
A new method was established for the preparation of both of the enantiomers of trans-4,5-dimethoxy-2-imidazolidinone (DMIm) via the Fe(III)-catalyzed oxidation of 2-imidazolone by H2O2-urea, which allowed the subsequent achievement o
Design, synthesis, single-crystal and preliminary antitumor activity of novel arenesulfonylimidazolidin-2-ones
Abdel-Aziz, Alaa A.-M.,El-Azab, Adel S.,El-Subbagh, Hussein I.,Al-Obaid, Abdulrahman M.,Alanazi, Amer M.,Al-Omar, Mohamed A.
, p. 2008 - 2014 (2012)
Novel series of 1-(arenesulfonyl)imidazolidin-2-one (3a-i) and 1,3-bis(arenesulfonyl)imidazolidin-2-one (5a-i) have been synthesized and tested for their antitumor activity against 60 tumor cell lines taken from nine different organs. A significant inhibi
Versatile chiral synthons for 1,2-diamines: (4S,5S)- and (4R,5R)-4,5-dimethoxy-2-imidazolidinones
Seo, Ryushi,Ishizuka, Tadao,Abdel-Aziz, Alaa A.-M,Kunieda, Takehisa
, p. 6353 - 6355 (2007/10/03)
(4S,5S)- and (4R,5R)-1-Acyl-4,5-dimethoxy-2-imidazolidinone derivatives, which are readily accessible from simple 1,3-dihydro-2-imidazolone heterocycles, represent good candidates for a new class of chiral synthons for use in the preparation of optically active threo-diamines such as 2S,3R- and 3S,4S-diamino carboxylic acids.
