875667-63-3

Upstream product

• 654682-18-5 1-(4-chlorophenyl)-2-(2,4-dichlorophenyl)ethanone 
• 1243243-28-8 C₁₉H₁₄Cl₃NO₂ 
• 952019-94-2 5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-2-carboxylic acid methyl ester 
• 122-01-0 4-chloro-benzoyl chloride 
• 122334-37-6 4-chloro-N-methoxy-N-methylbenzamide 
• 952019-92-0 5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-2,5-dioxo-pentanoic acid methyl ester 
• 952019-90-8 5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-2-hydroxy-5-oxo-pentanoic acid methyl ester 

Downstream Products

• 918294-12-9 5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-methyl-1H-pyrrole-2-carboxamide 
• 1243243-19-7 C₂₈H₂₉Cl₃N₄O₃ 
• 1243243-18-6 C₃₀H₂₆Cl₃N₃O₂ 

Relevant academic research and scientific papers

Rational design of a novel peripherally-restricted, orally active CB 1 cannabinoid antagonist containing a 2,3-diarylpyrrole motif

A new series of 2,3-diarylpyrroles have been prepared and evaluated as CB1 antagonists. Modulation of the topological polar surface area allowed the identification of high affinity peripherally-restricted CB 1 antagonists. Compound 1

DERIVATIVES OF 4,5-DIARYLPYRROLE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS

The invention relates to compounds having formula (I): Wherein X, R1, R2, R3, R4 and R5 are as defined herein. The invention also relates to the preparation method thereof and the use of same in thera

PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE

The invention concerns compounds of formula (I): Wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The invention also concerns the method

Regioselective synthesis of highly aryl-substituted pyrrole carboxylates as useful medicinal chemistry leads

The regioselective syntheses of two pharmaceutically relevant pyrrole scaffolds are described. A synthetic route for the preparation of differentially substituted pyrrole-3,4-dicarboxylates is presented and exemplified. This route circumvents some of the