87574-77-4

Upstream product

• 52786-52-4 4-chloro-N-(2,2,2-trifluoro-1-trifluoromethyl-ethylidene)-benzamide 
• 40683-75-8 5-(4-Chlorphenyl)-2,2,2-trimethoxy-3,3-bis(trifluormethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-en 
• 140-88-5 ethyl acrylate 
• 116177-78-7 N-<2,2-Difluoro-1-(trifluoromethyl)vinyl>-4-chlorobenzamid 

Downstream Products

• 78786-68-2 2-(4-Chlorophenyl)-5-fluoro-4-trifluoromethyl-oxazole 

Relevant academic research and scientific papers

UEBER DAS SYNTHESEPOTENTIAL TRIFLUORMETHYL-SUBSTITUIERTER ZINN-HETEROCYCLEN

4,4-Bis(trifluoromethyl) substituted heterodienes of type (F3C)2C=N-C(R1)=X (X = O, S, NR2) react with tin(II) compounds to give cycloadducts.The cycloaddition process causes an 'Umpolung' at the carbon

Cycloreversion Mechanism of 3,3-Bis(trifluoromethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-enes

2,2,2-Trimethoxy-3,3-bis(trifluoromethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-enes on thermolysis undergo a 1,3-dipolar cycloreversion reaction with formation of bis(trifluoromethyl) substituted nitrile ylides.Trapping reactions of the 1,3-dipolar species with α,β-unsaturated carboxylic acid esters and nitriles are described. 2-Aryl-3-carbethoxy-5,5-bis(trifluoromethyl)-1-pyrrolines obtained undergo an uncatalyzed autoxidation process to give 2-aryl-3-carbethoxy-3-hydroxy-5,5-bis(trifluoromethyl)-1-pyrrolines. 5,5-Difluoro-4-trifluoromethyl-2-oxazolines and 5-fluoro-4-tri fluoromethyl-oxazoles formed as by-products indicate that the thermal induced -cycloreversion reaction of 2,2,2-trimethoxy-3,3-bis(trifluoromethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-enes is most likely a stepwise process. - Keywords: -Cycloreversion Reactions, Trifluoromethyl Substituted 1,3-Dipoles, -Cycloaddition Reactions, 5,5-Difluoro-4-trifluoromethyl-2-oxazolines, 5-Fluoro-4-trifluoromethyl-oxazoles