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1,3-difluoro-2-phenylpropan-2-ol is an organic compound with the molecular formula C9H8F2O. It is a colorless liquid with a molecular weight of 172.16 g/mol. 1,3-difluoro-2-phenylpropan-2-ol is characterized by the presence of two fluorine atoms at the 1st and 3rd carbon positions, a phenyl group attached to the 2nd carbon, and a hydroxyl group at the 2nd carbon as well. It is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and reactivity. The compound is sensitive to moisture and should be stored under an inert atmosphere to prevent hydrolysis or other unwanted reactions.

876-43-7

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876-43-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 876-43-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,7 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 876-43:
(5*8)+(4*7)+(3*6)+(2*4)+(1*3)=97
97 % 10 = 7
So 876-43-7 is a valid CAS Registry Number.

876-43-7Relevant academic research and scientific papers

Asymmetric Desymmetrization via Metal-Free C?F Bond Activation: Synthesis of 3,5-Diaryl-5-fluoromethyloxazolidin-2-ones with Quaternary Carbon Centers

Tanaka, Junki,Suzuki, Satoru,Tokunaga, Etsuko,Haufe, Günter,Shibata, Norio

, p. 9432 - 9436 (2016/08/05)

We disclose the first asymmetric activation of a non-activated aliphatic C?F bond in which a conceptually new desymmetrization of 1,3-difluorides by silicon-induced selective C?F bond scission is a key step. The combination of a cinchona alkaloid based ch

CiF bond activation of unactivated aliphatic fluorides: Synthesis of fluoromethyl-3,5-diaryl-2-oxazolidinones by desymmetrization of 2-aryl-1,3-difluoropropan-2-ols

Haufe, Guenter,Suzuki, Satoru,Yasui, Hiroyuki,Terada, Chisato,Kitayama, Takashi,Shiro, Motoo,Shibata, Norio

supporting information, p. 12275 - 12279 (2013/02/23)

How to lose fluorine: Biologically relevant oxazolidinones 1 were synthesized through the desymmetrization of unactivated aliphatic difluorides by Si-induced catalytic CiF bond-cleavage using BSA/CsF (BSA=bis(trimethylsilyl) acetamide). The direct transfo

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