87604-52-2

Upstream product

• 100-39-0 benzyl bromide 
• 87604-45-3 (R)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pentan-1-ol 
• 87604-44-2 (S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pentan-1-ol 
• 100-44-7 benzyl chloride 
• 1093352-94-3 (2R)-1,2-O-isopropylidene-3-hydroxyheptan-1,2-diol 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 61981-46-2 Toluene-4-sulfonic acid (R)-3-benzyloxy-2-hydroxy-heptyl ester 
• 54620-74-5 (2R, 3RS)-(-)-1,2-epoxy-3-benzyloxyheptane 
• 61981-45-1 (2R, 3RS)-(+)-1,2,3-heptanetriol-3-benzylether 
• 94286-88-1 [2R,2(1R)]-2-(1-benzyloxy-pentyl)-oxirane 
• 94286-86-9 (2R,3R)-3-O-benzylheptane-1,2-diol 

Relevant academic research and scientific papers

Synthesis of the rarely obtained syn-Adducts in the Reaction of Organocopper Compounds with 2,3-O-Isopropylideneglyceraldehyde. Preparation of Optically Active Epoxy Alcohols

Organocopper compounds, prepared from Grignard reagents and copper(I) iodide in tetrahydrofuran-dimethyl sulphide, react with 2,3-O-isopropylideneglyceraldehyde highly stereoselectively (>10:1) affording the rarely obtained syn-addition products which can be readily converted into optically active epoxy alcohols, useful intermediates in organic synthesis.

ON THE STERIC COURSE OF THE ADDITION OF SOME ORGANOMETALLIC REAGENTS TO (R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE. SYNTHESIS OF OPTICALLY ACTIVE α-BENZYLOXY ALDEHYDES, ALCOHOLS, CARBOXYLIC ACIDS AND 1,2-DIOLS.

Organo-titanium and organo-zinc reagents were added stereoselectively to (R)-2,3-isopropylidene glyceraldehyde (1) to give the alcohols 2/3, which were converted into the optically active derivatives 4-11.