87614-69-5Relevant articles and documents
Improved Synthesis and Antitumor Evaluation of 5,8-Dideazaisofolic Acid and Closely Related Analogues
Hynes, J. B.,Yang, Y. C. S.,McGill, J. E.,Harmon, S. J.,Washtien, W. L.
, p. 232 - 235 (2007/10/02)
A new synthetic route to 5,8-dideazaisofolic acid (IAHQ) is described which precludes the possibility of contamination due to its 4-amino counterpart 5,8-dideazaisoaminopterin.Substitution of D-glutamic acid in this synthetic scheme gave D-IAHQ.The 9-form
