876299-47-7Relevant academic research and scientific papers
Synthesis of ent-Ketorfanol via a C-H Alkenylation/Torquoselective 6π Electrocyclization Cascade
Phillips, Eric M.,Mesganaw, Tehetena,Patel, Ashay,Duttwyler, Simon,Mercado, Brandon Q.,Houk, Kendall N.,Ellman, Jonathan A.
supporting information, p. 12044 - 12048 (2015/10/12)
The asymmetric synthesis of ent-ketorfanol from simple and commercially available precursors is reported. A RhI-catalyzed intramolecular C-H alkenylation/torquoselective 6π electrocyclization cascade provides a fused bicyclic 1,2-dihydropyridin
N-PYRAZOLYL CARBOXAMIDES AS CRAC CHANNEL INHIBITORS
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Page/Page column 51, (2010/11/05)
The present invention relates to amide compounds, processes for their preparation, pharmaceutical compositions containing these compounds and to their use in the treatment of disorders, conditions or disorders such as allergic disorders, inflammatory disorders and disorders of the immune system.
Triazolopyridinylsulfanyl derivatives as p38 MAP kinase inhibitors
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Page/Page column 31, (2008/06/13)
A compound of formula (I), or a pharmaceutically acceptable salt and/or solvate (including hydrate) thereof; and the use of a compound of formula (I) in the treatment of a TNF-mediated disease, disorder, or condition, or a p38-mediated disease, disorder, or condition, in particular the allergic and non-allergic airways diseases, more particularly obstructive or inflammatory airways diseases, preferably chronic obstructive pulmonary disease.
