876372-85-9

Upstream product

• 81228-09-3 2,4-difluorophenylacetic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1449112-26-8 3-(2,4-difluorophenyl)-1,1-dimethoxypropan-2-one 
• 1449112-27-9 C₁₆H₁₄F₂O₄S 
• 1449112-29-1 C₁₃H₁₆F₂O₂S₂ 
• 1449112-30-4 C₁₁H₁₀F₂O₃ 
• 1449112-31-5 C₁₂H₁₄F₂O₂S 
• 1326236-33-2 8-benzyl-2-(2,4-difluorobenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazine-3(7H)-one 
• 1449112-25-7 3-(2,4-difluorophenyl)-1-methoxy-1-(phenylthio)propan-2-one 
• 1449112-23-5 C₁₂H₁₂F₂OS₂ 
• 1449112-24-6 C₁₁H₁₂F₂OS₂ 

Relevant academic research and scientific papers

Chemical synthesis of coelenterazine and its analogs: New route by four segment-couplings

A novel and improved synthetic route includes four segment-couplings toward coelenterazine and its analogs as luminescent molecules. Regio- and chemo-selective cross coupling reactions using palladium catalysts with 5-iodo-3-bromo-2-aminopyrazine have enabled providing various aminopyrazine derivatives having different substituents. The improved synthesis of coelenterazine and its analogs employed advanced condensation with the aminopyrazines using various keto-acetal segments, which resulted in much higher yields to give the final imidazopyrazinone heterocycles than the previous method using keto-aldehydes.

N-HYDROXYACRYLAMIDE COMPOUNDS

This invention relates to novel N-hydroxyacrylamide compounds of formula (I) and pharmaceutically acceptable salts thereof . More particularly, it relates to novel N-hydroxyacrylamide compounds and pharmaceutically acceptable salts thereof which act as a