87657-60-1Relevant academic research and scientific papers
Stereoselective Synthesis of Cis-Substituted Azetidinones from Penicillin: a Formal Total Synthesis of Loracarbef
Deeter, Jack B.,Hall, David A.,Jordan, Christopher L.,Justice, Richard M.,Kinnick, Michael D.,et al.
, p. 3051 - 3054 (2007/10/02)
A new method for the synthesis of chiral azetidinones bearing a carbon-carbon bond at the 4-position is described.The preparation involves a stereoselective alkylation-reduction of a silylated 4-phenylsulfonyl azetidinone.The utility of this method was demonstrated by a formal total synthesis of loracarbef.
Process for preparing 4-substituted azetidinones
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, (2008/06/13)
A process for preparing 3-4-cis-β,β-(4)-substituted and 3-4-trans,β,α- (4)-substituted azetidinones is provided. Also provided are novel 4,4-disubstituted azetidinones.
