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Benzoic acid, 3-[(1E)-2-cyclopropylethenyl]-5-[methyl(methylsulfonyl)amino]-, methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

876593-45-2

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876593-45-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 876593-45-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,6,5,9 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 876593-45:
(8*8)+(7*7)+(6*6)+(5*5)+(4*9)+(3*3)+(2*4)+(1*5)=232
232 % 10 = 2
So 876593-45-2 is a valid CAS Registry Number.

876593-45-2Downstream Products

876593-45-2Relevant academic research and scientific papers

Conformationally biased P3 amide replacements of β-secretase inhibitors

Stachel, Shawn J.,Coburn, Craig A.,Steele, Thomas G.,Crouthamel, Min-Chi,Pietrak, Beth L.,Lai, Ming-Tain,Holloway, M. Katharine,Munshi, Sanjeev K.,Graham, Samuel L.,Vacca, Joseph P.

, p. 641 - 644 (2007/10/03)

We have synthesized and evaluated a series of conformationally biased P3 amide replacements based on an isophthalamide lead structure. The studies resulted in the identification of the β-secretase inhibitor 7m which has an in vitro IC50 = 35 nM

PHENYLCARBOXAMIDE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

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Page 53, (2008/06/13)

The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is a

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