217314-45-9

Usage

Uses

Used in Pharmaceutical Synthesis:
METHYL 3-AMINO-5-IODOBENZOATE is used as an intermediate in the synthesis of various pharmaceuticals for its unique chemical properties, including the presence of an amino and iodine atom, which can be leveraged in the development of new drugs.
Used in Agrochemical Synthesis:
In the agrochemical industry, METHYL 3-AMINO-5-IODOBENZOATE is used as a key component in the creation of pesticides and other agricultural chemicals, contributing to the effectiveness of these products in managing pests and diseases.
Used in Medicinal Chemistry Research:
METHYL 3-AMINO-5-IODOBENZOATE is utilized as a research compound in medicinal chemistry, where its structural features are studied for potential therapeutic applications and to understand its interactions with biological targets.

Upstream product

• 6313-17-3 3-iodo-5-nitro-benzoic acid 
• 618-95-1 methyl 3-nitrobenzoate 
• 50765-19-0 methyl 3-iodo-5-nitrobenzoate 

Downstream Products

• 217314-42-6 1-(3-iodo-5-methoxycarbonylphenyl)-2,5-dimethyl-1H-pyrrole 
• 847157-51-1 C₂₅H₃₀N₂O₅S 
• 1312535-59-3 N-[3-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-4-(trifluoromethyl)pyrimidin-2-amine 
• 943925-52-8 3-benzyloxycarbonylamino-5-iodo-benzoic acid methyl ester 
• 774478-86-3 2-(3-Benzyloxy-5-iodphenyl)aethylamin 
• 50765-26-9 3-Benzyloxy-5-iodbenzylcyanid 
• 50765-28-1 2-(3-Hydroxy-5-iodphenyl)aethylamin 
• 50765-25-8 3-Benzyloxy-5-iodbenzylchlorid 
• 50765-24-7 3-Benzyloxy-5-iodbenzylalkohol 
• 50765-23-6 3-Hydroxy-5-iodbenzylalkohol 
• 217314-43-7 1-(3-methoxy-5-methoxycarbonylphenyl)-2,5-dimethyl-1H-pyrrole 
• 217314-47-1 methyl 3-amino-5-methoxybenzoate 
• 929041-98-5 3-(2-cyclopropylvinyl)-5-[methyl(methylsulfonyl)amino]benzoic acid 
• 876593-45-2 3-((E)-2-Cyclopropyl-vinyl)-5-(methanesulfonyl-methyl-amino)-benzoic acid methyl ester 

Relevant academic research and scientific papers

Macrocyclic inhibitors of β-secretase: Functional activity in an animal model

A macrocyclic inhibitor of β-secretase was designed by covalently cross-linking the P1 and P3 side chains of an isophthalamide-based inhibitor. Macrocyclization resulted in significantly improved potency and physical properties when compared to the initia

Conformationally biased P3 amide replacements of β-secretase inhibitors

We have synthesized and evaluated a series of conformationally biased P3 amide replacements based on an isophthalamide lead structure. The studies resulted in the identification of the β-secretase inhibitor 7m which has an in vitro IC50 = 35 nM

PYRROLIDIN-3-YL COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to pyrrolidin-3-yl derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The i

1,3,5-SUBSTITUTED PHENYL DERIVATIVE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to 1,3,5-phenyl substituted derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

MACROCYCLIC BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is a

BENZYLETHER AND BENZYLAMINO BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to benzylether and benzylamino derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.