87682-04-0Relevant academic research and scientific papers
Anodic oxidation of monohalogenated phenols
Mori, Kazuki,Takahashi, Masakatsu,Yamamura, Shosuke,Nishiyama, Shigeru
, p. 5527 - 5532 (2007/10/03)
Anodic oxidation of simple o-halogenated phenol derivatives has been investigated. Among the oxidation products, tricyclic ketone 9 was obtained, along with both the corresponding diaryl ethers 3 and 4 and the diaryls 5-8. Additionally, the effect of the
Phenolic oxidation of o,o'-dihalogenated phenols
Takahashi, Masakatsu,Konishi, Hironori,Iida, Satoshi,Nakamura, Kensuke,Yamamura, Shosuke,Nishiyama, Shigeru
, p. 5295 - 5302 (2007/10/03)
A detailed inspection of phenolic oxidation products derived from the o,o'-dihalogenated cresol derivatives (1a - 1e) indicated that the bromo and chloro substituents promoted the oxidation leading to the corresponding diaryl ethers, whereas the iodo derivatives provided the diaryls. Selective reduction of 6d and its tyrosine derivative afforded the corresponding diaryl ethers carrying two chlorine atoms (14, 15). Interpretation of the selectivity of the phenolic oxidation was attempted by employing theoretical calculations.
